Abstract
Sugammadex (Bridion) represents a class named muscle relaxant encapsulator. It can be used to reverse the neuromuscular blockade induced by rocuronium or vecuronium in case of general anesthesia. Its molecular weight is 2.178 g/mol, with a structure consisting in a ring of eight negative charges. It has no receptor interaction in human body and it is eliminated via kidney, being contraindicated in end-stage kidney disease patients. Sugammadex has few side effects but there are same case reports about allergic reactions. Only three drugs can actually interact with sugammadex: toremifene, flucloxacillin and fusidic acid. It can be used in elderly and pediatric patients, in morbidly obese patients, patients with hepatic insufficiency or mild and moderate renal insufficiency or in muscular disease. Despite its beneficial use, the high price remains its main issue.
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