Sufentanil composite of different concentrations of ropivaeaine for obstetric epidural analgesia effect of clinical observation

Abstract

Objective To compare the different concentrations of 0.125 percent compound sufentanil ropivacaine for cesarean section patient controlled epidural analgesia (PCEA) clinical efficacy and adverse reactions. Methods 60 cases of combined spinal-epidural anesthesia downlink maternal cesarean section were randomly divided into three groups (n=20). Sufentanil 0.2 μg/ml respectively 0.125% ropivacaine (A) group, 0.4 μg/ml sufentanil 0.125% ropivacaine (B) group, 0.6 μg/ml respectively aufentanil 0.125% ropivacaine (C) group. Postop-erative PCEA line that is loading dose (5ml)+continuous dose (3ml/h) + PCA dose (1ml/times), lockout time 15min.Observation: (1) Records of the time 0～3, 3～6, 6～12, 12～24 h postoperative incision pain, uter-ine pain VAS score, squeeze the number of PCA. (2) Records 24h with the incidence of adverse reactions: nausea, vomiting, itching, motor block, drowsiness, respiratory depression.Results Obstetric after PCEA, 24h in patients with Sufentanil concentration increased, incision pain VAS score and contraction VAS pain score decreased, which B Group, C group and Cween the two VAS score was no significant difference (P>0.05). Surgery 3～6h, 6～12h and 24h push PCA total number, B Group, C group were significantly lower than that A group (P 0.05). PCEA24h with adverse reactions in the nausea, the incidence of pruritus with sufentanil increased concentration increases, C group and B Group, A group were significantly different (P 0.05). Three groups of vomiting, motor block, lethargy no significant difference (P>0.05), no respiratory depression. Conclusion The cesarean section PCEA, 0.4 μg/ml composite sufentanil 0.125% ropivacaine can get better analgesic effect and less side effects. Key words: Epidural analgesia; Concentration; Sufentanil; Cesarean section