Abstract

In this study, we performed the experiment of correlation between internal organ movement and external abdominal surface movement for the mini pig using the developed motion tracking system. The experimental system was consisted with imaging acquisition part and image signal analyzing part. The image acquisition of internal organ was performed with a C-arm fluoroscopy system, and abdominal surface images were acquired with a camera and image acquisition board. The signal processing of the image was conducted using LabVIEW 8.6. The developed system was applied to a mini pig. The information of the internal organ movement was acquired with C-arm fluoroscopy system by tracking the fiducial gold maker pre-implemented into diaphragm, which was used in Cyberknife radiation therapy. The data acquisition of internal organ movement due to respiration and abdominal surface movement was performed under general anesthesia. The motions of the internal and external markers were well correlated. The correlation coefficients between the AP movement of the external marker and the SI and RL movement of the internal target in the experiment using the mini pig were resulted in 0.903 and 0.905, respectively. It is confirmed that high correlations between the movements of external marker and the targetassigned in diaphragm in the experimental case for the mini pig were existed. Therefore, it is possible to predict the locations of internal target from the movement of the external marker. These results show the possibility to use the DTTRT (Dynamic Tumor Tracking Radiation Therapy) system of Korea Institute of Radiological and Medical Science (KIRAMS) to clinical application of animals.

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