Sudomotor function and obesity-related risk factors in an elderly healthy population: The PROOF–Synapse Study

Abstract

Autonomic nervous system (ANS) dysfunction that can be assessed through alterations of sweat function is a major risk predictor of all-cause mortality in the general adult population [1]. Obesity, metabolic syndrome (MS) and obstructive sleep apnea (OSA) have been recognised as risk factors for coronary heart disease (CHD) [2,3]. Whether these factors are related with ANS dysfunction as measured by sweat function, it has never been well established. Sudoscan has been developed to provide a quick, simple, non-invasive and quantitative assessment of sweat function [4,5].