Abstract

In approximately 80% of the infants who die unexpectedly in the first year of life no identifiable cause is found, and these infants are diagnosed with the sudden infant death syndrome (SIDS).1,2 The underlying cause is thought to be a combination of genetic predisposition and prenatal or postnatal environmental stressors.3 A failure to respond sufficiently to life-threatening hypoxic situation is commonly considered in various SIDS cases.4 A cardiac cause of death is also often suspected. Genetic testing efforts in SIDS cohorts have revealed genetic variants in cardiac genes.

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