Abstract
1. 1. A case of fatal anaphylactic shock following intradermal tests for allergy is reported. 2. 2. The pathological anatomy is described, consisting primarily of acute pulmonary emphysema of the so-called “guinea pig type” of anaphylactic reaction. 3. 3. Allergy tests are described which, by passive transfer and dilution studies, indict the cottonseed allergen as the cause of the fatal reaction. 4. 4. The importance of cottonseed allergen is discussed and its absence in commercial cottonseed oils and salad dressings is pointed out. 5. 5. The cases of anaphylactic deaths in the medical literature are reviewed. 6. 6. The advisability of preceding intradermal tests with scratch tests is advocated.
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