Abstract
The activity of succinic dehydrogenase (SDH) was examined in the gastric mucosa of 11 rats with normal body temperature (controls) and 11 rats with a body temperature maintained at 41-42° C for one hour in a thermostat. The pH of the mucosal surface of the glandular stomach was determined. The hyperthermic rats had an enlarged and congested gastrointestinal tract with a pH above 5 in the gastric content, whereas the stomachs of the controls were small and contracted with pH 1-2. No reduction was found in SDH activity of parietal cells that could account for the reduced hydrochloric acid secretion in hyperthermic animals.
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