Abstract

The subject of cow-pox vaccination was first studied by Jenner, in 1798. Following his work numerous other investigators took up the problem and many valuable additions were made to the earlier findings. The work of Jenner and his contemporaries was so complete and thorough that practically no clinical additions were made to their findings until the question was made the subject of an exhaustive study by von Pirquet, entitled, "Klinische Studien über Vakzination und Vakzinale Allergie" (1907). By means of exact measurements of the local lesions, associated with studies of the general reaction, and comparative tabulation of results, this author placed the entire subject on an exact scientific foundation which will serve as the basis for future work. The following work deals with a continuation of investigations in vaccinations based on the experiments performed by von Pirquet. <h3>METHOD OF VACCINATION</h3> The technic employed in the vaccination of this series of

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