Abstract
An 18-year-old man presented with enlarging masses in his right eye for months. Anterior segment examination revealed multiple pedunculated lesions extending the lower palpebral conjunctiva without corneal involvement (A). The fellow eye was uninvolved. We performed excisional biopsy combined with cryotherapy and injected interferon α-2a (IFN-α 2a) in subconjunctival space during the operation. The histopathological examination revealed papillary, well-differentiated, acanthotic nonkeratinized squamous epithelial cells with fibrovascular cores, which was compatible with conjunctival papilloma (B). After excision (C), we kept topical IFN-α 2a 4 times daily for 2 months. Three years later, no recurrence developed (D). (Magnified version of Figure A-D is available online at www.aaojournal.org).
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