Successfully Reducing Severe Asthma Exacerbations and Improving Asthma Control in a Pragmatic Study in African American/Black (AA/B) and Hispanic/Latinx (H/L) Patients with Moderate-Severe Asthma (PREPARE)

Juan Carlos Cardet,Joel Shields,Kartik Shenoy,Brianna Ericson,Elina Jerschow,Janet Robles,Suzanne Madisson,Jennifer Trevor,Maureen Fagan,Geoffrey Chupp,Opal Thompson,Sunit Jariwala,Paulina Arias Hernandez,Sylvette Nazario,Jean Kruse,Elliot Israel,Hazel Tapp,Ahmet Baydur,Diane Mckee,Lilin She,Ku-Lang Chang,Jacqueline Rodriguez-Louis,Gretchen Hammer,Magdalena Pasarica,Laura P Hurley ,R.a Calderon Candelario ,Paul M Stranges ,Paula J Busse ,Frank Rockhold ,Barbara Kaplan ,Nancy Maher ,Tamera Coyne‐Beasley ,Andrea J Apter ,Michael E Wechsler ,David C Kaelber ,Juan P Wisnivesky ,Alex D Colon-Moya ,Barbara P Yawn ,Brian Manning ,Isaretta Riley ,Victoria E Forth ,Jennifer Carroll ,Anne L Fuhlbrigge ,Víctor Pinto-Plata ,Wilson D Pace ,Thomas B Casale ,Cynthia S Rańd ,Michelle Hernández

doi:10.1016/j.jaci.2021.12.004

Abstract

Efforts to reduce the disproportionate asthma morbidity in African American/Black (AA/B) and Hispanic/Latinx (H/L) patients have been mostly unsuccessful. In a pragmatic, randomized study, we tested a Patient-Activated Reliever-Triggered Inhaled Corticosteroid (ICS) Strategy (PARTICS) in 1201 AA/B and H/L patients with moderate-to-severe asthma.

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