Abstract
Fluoroquinolones are no longer recommended for the treatment of gonococcal infections in the United States. Cephalosporins - ceftriaxone and cefixime - are the treatment of choice, as suggested by the Centers for Disease Control and Prevention (USA). There are limited data on the efficacy of cefpodoxime for the treatment of uncomplicated gonococcal infections. Two cases of HIV-infected homosexual men who were successfully treated with cefpodoxime for urethritis caused by Neisseria gonorrhoeae are described in the present study.
Highlights
Fluoroquinolones are no longer recommended for the treatment of gonococcal infections in the United States
Fluoroquinolone-resistant Neisseria gonorrhoeae is widely dispersed in the United States (US)
Other single-dose cephalosporins are suggested as alternatives, with oral cefpodoxime being the likely choice
Summary
Fluoroquinolones are no longer recommended for the treatment of gonococcal infections in the United States. Le traitement réussi d’une urétrite gonococcique sans complication chez des patients infectés par le VIH, au moyen d’une monodose de cefpodoxime par voie orale Les fluoroquinolones ne sont plus recommandées dans le traitement des infections gonococciques aux États-Unis. On possède peu de données sur l’efficacité du cefpodoxime pour le traitement des infections gonococciques sans complication.
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