Abstract
BackgroundMucormycosis is a rare fungal infection occurring chiefly in the lung or the rhino-orbital-cerebral compartment, particularly in patients with immunodeficiency or diabetes mellitus. Among Mucorales fungi, Rhizopus spp. are the most common cause of mucormycosis.Case presentationWe report a case of pulmonary mucormycosis caused by Rhizopus microsporus in a young patient with diabetes but no other apparent risk factors. The diagnosis mainly relied on clinical manifestation, positive pulmonary tissue biopsy, and fungal culture. The patient was successfully treated with posaconazole oral suspension and remains asymptomatic at one-year follow-up.ConclusionsPulmonary mucormycosis is a life-threatening condition and posaconazole is an effective treatment for pulmonary mucormycosis caused by Rhizopus microspores.
Highlights
Mucormycosis is a rare fungal infection occurring in the lung or the rhino-orbital-cerebral compartment, in patients with immunodeficiency or diabetes mellitus
Pulmonary mucormycosis is a life-threatening condition and posaconazole is an effective treatment for pulmonary mucormycosis caused by Rhizopus microspores
A retrospective review found that, in zygomycosis, the mortality for diabetes was 44%, whereas Pulmonary mucormycosis (PM) mortality increased to 76% [4]
Summary
Mucormycosis is a rare fungal infection occurring in the lung or the rhino-orbital-cerebral compartment, in patients with immunodeficiency or diabetes mellitus. *Correspondence: njukqt@163.com; sanghong@nju.edu.cn 2 Dept Dermatology, Sch Med, Jinling Hosp, Nanjing Univ, Nanjing 210002, People’s Republic of China Full list of author information is available at the end of the article caused by Rhizopus microsporus in a patient with diabetes mellitus. Yuan et al European Journal of Medical Research (2021) 26:131 the treatment changed, a reexamination of thoracic CT showed patchy consolidation in both lungs with pulmonary cavitation formation (Fig. 1a).
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