Successful Treatment of Olfactory Neuroblastoma with IMRT: a Case Report

Abstract

Olfactory neuroblastoma (ONB) is a rare and aggressive tumor of the olfactory mucosa that has been traditionally treated with radical surgical excision. Nevertheless, these rare tumors are still associated with high rate of recurrence and mortality. Here in, I report a novel therapeutic approach using intensity modulated radiotherapy (IMRT). IMRT in conjunction with weekly cisplatin should be considered in patients with unresectable olfactory neuroblastoma since this technique can deliver an adequate tumoricidal dose. Careful IMRT treatment planning is necessary to avoid or minimize untoward side effect.