Abstract
BackgroundNivolumab is effective for gastric cancer and lung cancer, but complete response is rare. We experienced a case of synchronous gastric cancer and lung cancer who was treated by nivolumab and laparoscopic gastrectomy.Case presentationA 63-year-old male consulted our institution and was found to have gastric cancer cT1(SM)N0M0 Stage IA and lung cancer cT2N2M1(PUL) Stage IV. He received eight chemotherapy treatments plus radiation, but the lung disease remained progressive. Finally, he received nivolumab therapy and complete response of both cancers was obtained. The gastric cancer recurred, but was successfully treated by laparoscopic gastrectomy. The resected specimen revealed three lesions, each being pT1aN0M0 Stage IA. The primary gastric cancer seemed to have completely vanished without scarring.ConclusionsThis was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab.
Highlights
Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare
This was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab
Nivolumab is a medication used to treat a number of types of cancer, including melanoma, lung cancer, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, gastric cancer, and esophageal cancer, among others
Summary
Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare. Conclusions: This was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab. *Correspondence: shunji.endo@hosp‐yao.osaka.jp 1 Department of Digestive Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701‐0192, Japan Full list of author information is available at the end of the article
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