Abstract
BackgroundInfective endocarditis is one of the most common infections among intravenous drug addicts. Its complications can affect many systems, and these can include acute renal failure. There is a scarcity of cases in the literature related to acute renal failure secondary to infective endocarditis treated with peritoneal dialysis. In this paper, the case of a 48-year-old Saudi male is reported, who presented with features suggestive of infective endocarditis and who developed acute kidney injury that was treated successfully with high tidal volume automated peritoneal dialysis. To our knowledge, this is the second report of such an association in the literature.Case presentationA 48-year-old Saudi gentleman diagnosed to have a glucose-6-phosphate dehydrogenase deficiency and hepatitis C infection for the last 9 years, presented to the emergency department with a history of fever of 2 days’ duration. On examination: his temperature = 41 °C, there was clubbing of the fingers bilaterally and a pansystolic murmur in the left parasternal area. The results of the blood cultures and echocardiogram were supportive of the diagnosis of infective endocarditis, and the patient subsequently developed acute kidney injury, and his creatinine reached 5.2 mg/dl, a level for which dialysis is essential for the patient to survive.ConclusionHigh tidal volume automated peritoneal dialysis is highly effective as a renal replacement therapy in acute renal failure secondary to infective endocarditis if no contraindication is present.
Highlights
Infective endocarditis is one of the most common infections among intravenous drug addicts
High tidal volume automated peritoneal dialysis is highly effective as a renal replacement therapy in acute renal failure secondary to infective endocarditis if no contraindication is present
High tidal volume automated peritoneal dialysis (APD) can be effective as a renal replacement therapy in acute kidney injury (AKI) secondary to infective endocarditis provided no contraindication is present
Summary
High tidal volume APD can be effective as a renal replacement therapy in AKI secondary to infective endocarditis provided no contraindication is present. Authors’ contributions AMO, IMZ, AAA, EMO, SMH: analyzed and interpreted the patient data regard‐ ing the nephrology disease and infectious disease. FAM, AKH: wrote about the peritoneal dialysis in the discussion, and was a major contributor in writing the manuscript. All authors carried out the literature review and drafted the manuscript. All authors read and approved the final manuscript. Author details 1 Department of Internal Medicine, The University of Dammam, Prince Saud bin Fahd Street, PO Box 3669, Khobar 31952, Saudi Arabia. Department of Internal Medicine, University of Dammam, PO Box 2435, Dammam 31451, Saudi Arabia. Nephrology Division, Department of Internal Medicine, Univer‐ sity of Dammam, PO Box 2435, Dammam 31451, Saudi Arabia
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