Abstract
Successful Treatment of A Primary Cervical Diffuse Large B-Cell Lymphoma with Rituximab-CHOP Immunochemotherapy
Highlights
Primary Large B-cell lymphoma of the cervix is a very rare disease
Therapy is still under discussion but chemotherapy with R-CHOP or CHOP-like regimens are suitable with a better prognosis and high overall survival
In the case of a young woman with a large well defined uterine cervical mass, bilateral ureteral entrapment and an uncertain Pap or biopsy tests, the presence of a lymphoma should be considered among other rare tumors
Summary
The aim is to provide an updated review in the issue and report a recent case in our institution. Case report: We describe a 46-year-old healthy woman with primary extranodal non-Hodgkin’s diffuse large B-cell lymphoma (DLBCL) of the uterine cervix Ann Arbor stage IIEA IPI 1. The patient presented an acute renal failure and severe ureterohydronephrosis due to a large cervical mass. She was successfully treated with 6 courses of multidrug therapy based on Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) with no major side effects
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