Abstract
It has been recently discovered that somatic cells can be reprogrammed into iPSC's by transgenic expression of a key transcription factors (OCT4, SOX2, KLF4, and cMYC). These iPSC's mimic the pluripotent state observed for human embryonic stem cells (ESC's) and have the advantage that human embryos are not needed, thus circumventing potential ethical concerns. In addition, this reprogramming technology has the potential to generate patient-specific iPSC's for future cell therapy or disease modeling to develop novel therapies for infertile patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
