Abstract

BACKGROUND: Corifollitropin alfa is a new recombinant fertility hormone that is able to initiate and sustain follicular growth for an entire week and replaces seven daily injections of gonadotropins. Accordingly, this is a further improvement of the simplified, patient-centered GnRH antagonist regimen. The development program of corifollitropin alfa consisted of several trials that showed that the drug was safe and efficacious in terms of the number of oocytes obtained and ongoing pregnancy rates.

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