Abstract
The aim of this study was to report the efficacy of nitempiram against Cochiliomiyia hominivorax larvae in ocular myiasis in a naturally infested dog. A female Beagle dog with occular miyasis was attended. After care and clinical examination, was found involvement of the entire ocular and periocular region. The animal was treated with nitenpyram, with a dose of 4,7 mg/kg, orally, jointly with analgesic medication. The expulsion and fall of live and dead larvae were evaluated, which were quantified every 15 minutes in the first hour and thereafter at 2, 3, 4, 6, 18 hours after treatment and subsequent manual removal of the larvae. Overall effectiveness was calculated, the larval expulsion rate and the larvicidal effect of nitenpyram. In full there were 140 larvae in the lesion, from which 90 live larvae were expelled, 46 dead larvae and 4 dead larvae mechanically removed, presenting 100% overall effectiveness, with larval expulsion activity of 97.1% and larvicidal efficacy of 35.7%. Based on the results obtained in this case, it can be concluded that nitenpyram has a fast-acting and safe action under C. hominivorax larvae, proving be a pleasant alternative therapeutic alternative for the elimination of myiasis in orbital cavity of dogs.
Highlights
Myiasis is a disease characterized by infection by dipterous larvae, mainly occurring in tissues and cavities of humans and animals (Han et al, 2018a)
We report the treatment with nitenpyram of a naturally infested dog suffering from extensive myiasis of the ocular bulb caused by C. hominivorax larvae
Nitenpyram is rapidly absorbed by the gastrointestinal tract, so it has fast action, as indicated by the hyperexcitation observed in the larvae after 15 minutes of treatment, and the increase of head wiggling by the dog, probably due to the discomfort caused by the movement of the excited parasites in the orbital cavity, 30 minutes after the drug administration
Summary
Myiasis is a disease characterized by infection by dipterous larvae, mainly occurring in tissues and cavities of humans and animals (Han et al, 2018a). Accepted: January 23, 2020 The study was carried out at Laboratório de Quimioterapia Experimental em Parasitologia Veterinária – LQEPV Animal Parasitology Departamento de Parasitologia Animal - DPA– ADP, Universidade Federal Rural do Rio de Janeiro – UFRRJ
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