Abstract

Diffuse sclerosing osteomyelitis of the manidble ( DSMO) is a form of chronic non-bacterial osteitis (CNO) and predominantly affects patients < 18 years. It can result in cosmetic disfigurement. No uniformly effective treatment exists. Intravenous pamidronate (IV-PAM) has been reported to be effective in multifocal CNO.

Highlights

  • Diffuse sclerosing osteomyelitis of the manidble ( DSMO) is a form of chronic non-bacterial osteitis (CNO) and predominantly affects patients < 18 years

  • A 4-year old Caucasian female was diagnosed with DSMO and prospectively followed from 2007-2014

  • Naproxen was of no benefit and she was started on monthly 1-day Intravenous pamidronate (IV-PAM)

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Summary

Introduction

Diffuse sclerosing osteomyelitis of the manidble ( DSMO) is a form of chronic non-bacterial osteitis (CNO) and predominantly affects patients < 18 years. Intravenous pamidronate (IV-PAM) has been reported to be effective in multifocal CNO

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