Abstract
PROF. R. ROBINSON and Mr. G. R. Ramage in a recent letter1 state that they are engaged in the synthesis of certain substituted βγ-diphenyladipic acids and of certain derivatives of chrysene. I have been working in this field for some years and work in progress, or projected, in part in collaboration with research students, includes the synthesis of substituted βγ-diphenyladipic acids derived from o-, m-, and p- chloro-, bromo-, iodo-, hydroxy-, methoxy-, nitro-, amino- and dimethylamino- benzaldehyde and from veratrole and piperonal via the benzylidene malonic esters2 and cinnamic esters3 with the object of (a) effecting the optical resolution of both forms, (b) their conversion into derivatives of chrysene4, and (c) their conversion into derivatives of possible therapeutic and industrial value. The research on the reduction of substituted cinnamic esters has been assisted by grants from the Chemical Society in June 1930 and 1931.
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