Abstract
A clinical dilemma is how to clearly differentiate a substance-induced psychotic disorder (SIPD) from a primary psychotic illness or a psychotic illness with comorbid substance use. Symptoms of SIPD include but are not limited to paranoia and hallucinations, negative symptoms, disinhibition or dreaminess, and/or sensations of heightened awareness. In cocaine use, there also exist paranoid delusions and hallucinations. While there is no definitive standard of treatment to address SIPD, management of such disorders tends to vary depending on substances used, clinical symptomatology, dosage, frequency, and chronicity, among other variables. Given that the relationship between SIPD and the development of several mental illnesses is well established, a long-term follow-up period is needed to identify, prevent, and effectively treat further relapses. [ Psychiatr Ann . 2023;53(4):166–170.]
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