Abstract
The division of anti-M and anti-N antibodies into subspecificities based on dependence of the epitope on amino acid residue 1 or 5 of GPA, amino groups and sialic acid residues is presented. The Workshop antibodies were classified into the subspecificities by testing their reactivity with GPA-M or GPA-N untreated and modified by Edman degradation (release of the first amino acid residue), periodate oxidation, N-acetylation and desialylation. Most antibodies, according to former results, belonged to the group recognizing the blood group M- or N-related epitope dependent on the first amino acid residue, amino group and sialic acid residues, but other subspecificities were also found.
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Schedule a callMore From: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
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