Abstract
A nucleoside reverse transcriptase inhibitor (NRTI) backbone remains standard in combination antiretroviral therapy, but there is ongoing interest in developing NRTI-sparing regimens to avoid the drugs' short- and long-term toxicities. In a recent multinational, open-label, manufacturer-sponsored trial, 121 treatment-naive HIV-infected individuals with confirmed CCR5-tropic virus were randomized to receive ritonavir-boosted atazanavir in combination with either tenofovir/FTC or …
Published Version
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