Abstract
ABSTRACTStudy Objective: Design: Setting: Paricipants: Measurements: Results: Conclusions: Key words: aged, 75 years and over; subjective memory impairment; prospective study; dementiaElderly persons expressing a worsening of memory function are at increased risk ofdeveloping dementia.When adjusting for potential confounding by depressive symptoms, two of the GMSquestions scored at baseline, 'Is it more difficult to remember things than it used to be?' and 'Do youwrite reminders to yourself more often now than before?', were significant predictors of dementiawithin three years, OR = 3.3, 95% CI = 1.2–8.6 and OR = 2.8, 95% CI = 1.0–7.6, respectively.Dementia (DSM-III and DSM-III-R criteria).285 non-demented persons aged 75 years and above at start of study, 77.5% women.Persons living at home.Prospective study of a random sample of older people with follow-ups after three, six, nineand twelve years.To assess whether complaining of memory impairment, as measured by the subjectivepart of the Geriatric Mental State examination (GMS, the Canberra community version), predictslater development of dementia.
Highlights
Complaints about reduced memory function are frequent among elderly people [1,2]
Studies of the relationship between a subjective feeling of a reduced memory function and objective memory impairment in elderly persons have led to ambiguous conclusions
Having one or more memory problem was reported by 36.5%
Summary
Complaints about reduced memory function are frequent among elderly people [1,2]. Studies of the relationship between a subjective feeling of a reduced memory function and objective memory impairment in elderly persons have led to ambiguous conclusions. Few studies have been carried out to examine whether subjective memory impairment predicts later development of dementia. Flicker [8] found that elderly people with a subjective perception of cognitive decrement were not at a high risk of worsened cognitive function during the subsequent 3-4 years. O'Brien et al [9] showed that among subjects with memory complaints, nearly 10% developed dementia during the following three years
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