Abstract
To evaluate sleep disorders and daytime drowsiness in a cohort of patients affected by anorexia nervosa and their impact on health-related quality of life. We evaluated patients affected by restricting-type of anorexia nervosa (AN-R) and healthy controls by the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, Beck Depression Index. We also used the Short-Form Health Survey (SF-36) questionnaire to assess the quality of life in both AN-R and controls. Twenty-eight out of 34 AN-R patients (82.3%) in contrast with ten out of 34 healthy subjects (29.4%) had a pathological PSQI score compared to HC (p < 0.0001). The overall PSQI score (p <0.001), sleep quality (p <0.001), sleep duration (p = 0.02), sleep efficiency (p = 0.002), sleep disturbances (p = 0.03) and daytime dysfunction (p = 0.004) were significantly higher in AN-R than in controls. SF36 showed significantly reduced scores of standardized physical components (p = 0.01) and standardized mental components (p < 0.001), physical function (p < 0.001), physical role (p < 0.001) and general health (p < 0.001), vitality (p < 0.001), social functioning (p < 0.001) emotional role (p = 0.001) and mental health (p < 0.001) in AN-R. We found a significant correlation between the PSQI score and both the physical role (r = -0.35, p = 0.03) and level of education (r = 0.38, p = 0.02). Our data showed reduced overall sleep quality without excessive daytime sleepiness in AN-R. Sleep quality correlated significantly with quality of life (physical role) and level of education.
Highlights
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by refusal to maintain proper body weight, an intense fear of gaining weight despite the patients are underweight due to a distorted perception of body image
The control group consisted of 34 women matched for age
The group of patients (AN) showed a significantly lower BMI compared with controls (p
Summary
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by refusal to maintain proper body weight, an intense fear of gaining weight despite the patients are underweight due to a distorted perception of body image. AN include two different subtypes; the restricting-type (AN-R) and the Binge-Eating/Purging Type. In AN-R, a reduction in food intake without binge-eating or purging behaviour accomplishes weight loss [2,3]. Sleep disorders are frequently associated with psychiatric diseases [4]. The early recognition of sleep complaints and their management may improve the outcome of the disease itself and prevent psychiatric illness relapse[4,5,6,7]. AN is often associated with sleep impairment, despite a few studies on the prevalence of sleep disturbances in AN [7]. Hypothalamic dysregulation might impair the sleep and eating homeostasis by anorexigenic and orexigenic hormones [7,9,10,11,12,13]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
