Abstract
Subgemmal neurogenous plaques are characterized as anatomic neural aggregates of ganglion cells and nerve plexus frequently associated with taste buds of the tongue. A 63-year-old male patient was referred to the oral medicine clinic presenting with severe pain and burning sensation in the tongue. Extra-oral examination revealed no alteration. Intra-oral examination showed an erythematous area, with pain sensation, measuring 2 × 2 mm, with 3 months of evolution, localized on the right posterior border of the tongue. The patient reported hypertension anddiabetes. An excisional biopsy was performed under local anesthesia. Microscopic examination revealed a mucosa covered by squamous epithelium with anatomic conformation of lingual papilla, associated with taste buds. Neural cell bundles and chronic inflammatory infiltrate were observed in the lamina propria. Immunohistochemistry was diffusely positive for S100. The diagnosis was subgemmal neurogenous plaque, and the patient was free of symptoms after 21 days. Support: CAPES
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