Abstract

Subependymal giant cell astrocytoma is a relatively infrequently encountered tumor of astrocytic derivation that most commonly arises in the region of the foramen of Monro and may extend into either the lateral ventricle or third ventricle. Because of location, the most common clinical presentations are related to signs and symptoms of increased intracranial pressure. There is a well-established association of this lesion with tuberous sclerosis, and it has been hypothesized that these tumors might evolve from enlargement of subependymal hamartomatous nodules which are quite frequently found in tuberous sclerosis (1–3). The radiographic appearance of the lesion is often that of an intraventricular based tumor with variable amounts of calcification and variable degrees of enhancement (1,4).Concomittant hydrocephalus is frequently noted. In the setting of tuberous sclerosis, smaller periventricular nodules, corresponding to small subependymal hamartomatous lesions, are frequently seen.

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