Abstract

Researchers at the University of Amsterdam, the Netherlands, evaluated the occurrence, treatment, and outcome of subdural empyema as a complication of community-acquired bacterial meningitis in 28 (2.7%) adults.

Highlights

  • Serum N-glycosylation screening and/or enzyme analysis of DPM synthase are recommended in the workup of infants born with unsolved dystroglycanopathies

  • Five patients with empyema causing midline shift were treated by neurosurgical evacuation of the empyema

  • In patients suspected of having developed subdural empyema, the diagnosis was confirmed by MRI with diffusion-weighted imaging

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Summary

Introduction

In a pediatric study of intracranial empyema at the University of Paris Descartes, 33 of 38 patients presented with subdural empyema and 5 with extradural empyema. Serum N-glycosylation screening and/or enzyme analysis of DPM synthase are recommended in the workup of infants born with unsolved dystroglycanopathies. Researchers at the University of Amsterdam, the Netherlands, evaluated the occurrence, treatment, and outcome of subdural empyema as a complication of community-acquired bacterial meningitis in 28 (2.7%) adults. Predisposing conditions in 26 (93%) patients included spread of otitis or sinusitis to the subdural space in 21 (75%).

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