Subcutaneous Malignant Melanoma developing in Congenital Giant Naevus with Complete Spontaneous Regression of Superficial Dermo-Epidermal Part:A Case Report

Sohini Roy Debarati

doi:10.4172/2376-0427.1000196

Abstract

Giant congenital melanocytic nevi a ≥ 20 cm is rare in adolescents and adults. Here we present a case of subcutaneous melanoma developing in congenital giant naevus with complete regression of superficial dermoepidermal part. A 17 yr old girl presented with a painless and gradually increasing swelling in her right temporal region on pre-existing giant congenital menocytic naevus (GCMN) on right hemiface. FNAC proved the case as malignant melanoma of temporal region with metastatic deposit in cervical lymph node. On histopathological examination it was found that the melanoma arising deep in the subcutaneous tissue with extensive involvement of deeper structures, extensive metastasis of cervical lymph nodes, salivary glands, deeper soft tissues with spontaneous regression of superficial epidermal and dermal part. Though regression is seen in melanomas, spontaneous regression has been mostly seen in melanomas with only intraepidermal component.

Highlights

Giant congenital melanocytic nevus is a variant of congenital naevus characterised by its extensive size, by definition the surface area being 144 cm2 or larger
We present a case of aggressive subcutaneous malignant melanoma in a giant congenital naevus with spontaneous regression of superficial part without any treatment
Though regression is seen in melanomas, spontaneous regression has been mostly seen in melanomas with only intraepidermal component [2]

Summary

Introduction

Giant congenital melanocytic nevus is a variant of congenital naevus characterised by its extensive size, by definition the surface area being 144 cm2 or larger. Congenital giant naevi extend into deeper tissue layers with involvement of neurovascular and deep striated muscle bundles. In contrast melanomas arising in GCMN often extend into deeper tissues. We present a case of aggressive subcutaneous malignant melanoma in a giant congenital naevus with spontaneous regression of superficial part without any treatment. She had a congenital giant naevus on the right side of her face (Figure 1).

Results

Conclusion