Abstract
Abstract Subcritical water chromatography (SBWC) refers to a new reversed‐phase liquid chromatography (RPLC) technique where high‐temperature water is used as the sole mobile phase component. The major advantage of SBWC is the elimination of toxic mobile phase organic solvents required in traditional RPLC. These organic solvents are not only expensive in terms of purchasing price but also costly in their waste disposal. Therefore, the SBWC technique offers both economical and environmental benefits. Additional advantages of SBWC are fast analysis time; temperature‐dependent efficiency, selectivity, and resolution; temperature‐programmed elution; and ability to accommodate both gas‐ and liquid‐phase detectors. Most importantly, after years of academic studies, industry started paying attention to this economical and green separation technique. For example, Procter & Gamble has recently funded an SBWC project in developing green SBWC methods for the analysis of skincare products.
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