Abstract
Subcorneal pustular dermatosis (SPD) is a chronic, relapsing vesiculopustular eruption that typically affects the trunk and intertriginous areas and usually occurs in women more than 40 years of age. 1 Sneddon IB Wilkinson DS. Subcorneal pustular dermatosis. Br J Dermatol. 1979; 100: 61-68 Crossref PubMed Scopus (104) Google Scholar We describe a case of SPD in a patient with aplastic anemia induced by antituberculosis medications. Although the association of SPD with paraproteinemia, myeloma, and inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease has been recognized, 2 Kasha EE Epinette WW. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) in association with a monoclonal IgA gammopathy: a report and review of the literature. J Am Acad Dermatol. 1988; 19: 854-858 Abstract Full Text PDF PubMed Scopus (83) Google Scholar , 3 Delaporte E Colombel JF Nguyen-Mailfer C et al. Subcorneal pustular dermatosis in a patient with Crohn’s disease. Acta Derm Venereol (Stockh). 1992; 72: 301-302 PubMed Google Scholar an association with aplastic anemia has not been previously reported.
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