Subakut Tiroiditte Prognoz Öngörülebilir mi?

Abstract

Aim: Subacute thyroiditis (SAT) is a thyroid disease that seriously affects the quality of life for patients
 caused by acute inflammation of the thyroid gland. Apart from classical acute phase reactants, the values
 and rates obtained from peripheral blood count (mean platelet volume (MPV), neutrophil-to-lymphocyte
 ratio (NLR), and platelet-to-lymphocyte ratio (PLR)) values are also accepted as practical indicators
 of systemic inflammation. Our aim in this study is to compare the effects of systemic inflammation
 markers and the treatments given in the laboratory tests of our patients with a diagnosis of SAT, on the
 hypothyroid state one year later.
 Material and Methods: In this study, which was carried out with a retrospective method, 133 patients
 were included in the study. The medical data of these patients at the time of SAT diagnosis and one
 year later were analyzed. 37 patients were in the steroid group and 97 patients were in the nonsteroidal
 anti-inflammatory drug (NSAID) group.
 Results: The male/female ratio was similar in both groups. Female dominance was observed in both
 groups in patients diagnosed with SAT. The thyroid tests of the groups, which were hyperthyroid at the
 beginning and euthyroid one year later, were similar between the groups (p>0.05). Both groups had
 an increase in acute phase reactants at baseline (erythrocyte sedimentation rate [ESR] and C-reactive
 protein (CRP) levels) and normalized after treatment. Neutrophil (p0.05) and
 platelet (p0.05).
 Conclusion: Inflammation markers and treatments applied in SAT patients did not have a significant
 effect on the prognosis