Abstract
Subacutesclerosingpanencephalitis(SSPE) is a late complication of measles virus infection. It presents with psychiatric manifestation, progressive dementia, myoclonic jerk and other focal neurological signs. The diagnosis is based upon characteristics clinical manifestation, the presence of characteristic periodic EEG discharge, and demonstration of raised antibody titer against measles in plasma and cerebrospinal fluid. In our case patient presented with behavioral change, myoclonic jerk, characteristic EEG and elevated level of antibody both in serum and CSF.DOI: http://dx.doi.org/10.3329/jom.v16i1.22403 J MEDICINE 2015; 16 : 51-52
Highlights
Subacutesclerosingpanencephalitis (SSPE) was first described by Dawson in 1933-1934 as sub acute inclusion encephalitis
Fever was associated with maculopapular rash all over the body which disappeared after few days and was associated with cough, coryza and conjunctivitis
Fever subsided after 5 days; thereafter he developed severe vomiting not responding to medication
Summary
Subacutesclerosingpanencephalitis (SSPE) was first described by Dawson in 1933-1934 as sub acute inclusion encephalitis. Patient’s mother gave history about infrequent small jerky movement of the whole body from the onset of fever but this abnormal movement gradually increased in frequency and severity. He came from a low socioeconomic condition and has incomplete vaccination status. His parents could not specify whether measles vaccine was given or not On query, his mother gave history of maculopapular rash associated with fever at the age of 5 yrs. On general examination patient was bed ridden due to generalized rigidity and frequent jerky movements. Frequent repetitive jerky movements of the whole body more on the left side were present. Measles virus antibody in blood IgG positive, IgM negative. Measles virus Antibody in CSF IgG: Positive (AI: 4.26), Ref value (AI: 1.0).
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