Subacute de Quervain's thyroiditis: clinical and pathomorphological features of patients operated on thyroid gland.

Abstract

Background. An annual increase in the number of patients with endocrine pathology is observed in Ukraine. SubacutedeQuervain's thyroiditis is a rare inflammatory disease of thyroid gland of viral etiology which on average occurs in 3 - 6% of cases among all thyroid pathology. Objective – to study clinical and pathomorphological features of Subacute de Quervain's thyroiditis of patients operated on thyroid gland in the last ten years. Меthods. Analysis of archival data results of pathohistological reports on the patients operated on thyroid gland in Lviv Regional Clinical Hospital in 2006-2015 and medical histories with diagnosed cases of Subacute de Quervain's thyroiditis was conducted. In ten years’ time 5587 cases of patients operated on thyroid gland pathology have been revealed, among them 17 cases of Subacute de Quervain's thyroiditis which is 0,3% from all thyroid diseases. There were only women among the patients and their average age was 56. Results. While studying the medical histories it was revealed that the most frequent women’s complaints were the following: feeling of a foreign body in the neck area, discomfort when swallowing, bulging on the front of the neck, dyspnea, general weakness. Subacute de Quervain's thyroiditis was not diagnosed clinically in any case, and in one third of the cases there was a suspicion of malignant thyroid tumor. Pathoanatomical diagnosis in half of the cases was combined and often Subacute de Quervain's thyroiditis was combined with a multi-nodule colloid goiter. Conclusion. Subacute de Quervain's thyroiditis is a rare pathology of thyroid gland without sufficiently characteristic pathognomonic signs that makes clinical diagnostics rather difficult. Thoroughly collected anamnesis and conducting of appropriate laboratory tests including ultrasonic diagnostics of thyroid gland help to diagnose Subacute de Quervain's thyroiditis.