Abstract
Diabetes mellitus is a chronic metabolic disease, which is not able to secrete insulin in sufficient quantities or the body is unable to use insulin effectively so there is an excess glucose level and immediately suffer from some complications against the organs. Diabetes mellitus can be cured by herb utility which are thought to have compounds that has an antidiabetic effect. Therefore, this literature study discusses the antidiabetic activity of orange peel (Citrus sp.). The literature search was carried out on the Google Scholar search engine which used some keyword included antidiabetic, extract, orange peel, Citrus. In this literature study, there are inclusion and exclusion criteria for selecting journals as literature sources. The results of 12 literatures review that orange peel had antidiabetic activity by decrease blood glucose levels in some animal trials that had received an effective dose of orange peel extract in each of the reviewed studies. Hence, it can be concluded that various type of Citrus peels has antidiabetic effect.
Highlights
PENDAHULUAN Diabetes mellitus merupakan penyakit metabolik yang berlangsung kronik dimana penderita diabetes tidak bisa memproduksi insulin dalam jumlah yang cukup atau tubuh tidak mampu menggunakan insulin secara efektif sehingga terjadilah kelebihan gula di dalam darah dan baru dirasakan setelah terjadi komplikasi lanjut pada organ tubuh (Khairani, 2014)
Diabetes mellitus can be cured by herb utility
this literature study discusses the antidiabetic activity of orange peel
Summary
Kulit jeruk lemon 328 mg/kgBB Induksi Aloksan (Neovita et al, 2021). (Citrus limon (L.)). Namun pada kelompok konsentrasi ekstrak kulit jeruk yang tinggi (150mg/kgBB) terjadi penurunan glukosa puasa yang paling besar dan signifikan dengan nilai (P
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