Abstract

the open group; also not statistically significant (P = 0.12). No age difference occurred between the worsened scores group and stable scores group; older age was not associated with POCD. IL-6 levels were higher in the open vs. laparoscopic group (P <.0001). Conclusion: In this pilot study, the average incidence of POCD was not statistically different between elderly subjects undergoing open vs. laparascopic surgery. Age did not influence the occurrence of POCD. Although inflammatory markers were significantly higher in the open group, consistent with a higher degree of stress response, the open group did not have higher rates of delirium. This association is worth investigating in a larger sample size.

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