Abstract

Surveillance programs of patients with head and neck cancer (HNC) detect synchronous or metachronous esophageal squamous cell carcinoma (ESCC) in up to 15% of the patients. The detection of ESCC in patients with HNC at early stage is desirable since it affects prognosis. Endoscopic surveillance of the esophagus with narrow band imaging (NBI) or Lugol chromoendoscopy presents high sensitivity but low specificity for the detection of early ESCC. Esophagitis may also present as Lugol-unstained areas.

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