Su1549 Colonic Preparation Before Colonoscopy: Evaluation of a New Method With Intracolonic Infusion of Water Compared to Classical Administration of PEG

Abstract

Bowel cleansing before colonoscopy is currently based upon lavage solutions of polyethylene glycol (PEG) or NaP with large amounts of fluids ingested in a splitted manner. This prospective randomized study compared a PEG protocol with a new method of bowel cleansing based upon infusion of water into the colon at low pressure (PrepSystem, novoGI, Netanya, Israel). Patients and Method: The device for water infusion (novoGI, Lifestream, Austin, TX) is made of a reservoir of water maintained at 37°C. The patient is installed on an adapted seat allowing easy evacuation of water and faeces. Water is infused by gravity through a cannula, into the rectum. Patients with an indication of colonoscopy and no history of colorectal surgery or IBD were randomly assigned to PEG preparation (2L PEG in the evening before and 2L in the morning of colonoscopy) or the Prepsystem. All patients followed a low residue diet for 5 days. In the Prepsystem group, sennosides (Pursennide 80mg, Novartis, Rueil Malmaison, France) were administered in the evening before and patients underwent 2 cleansing cycles, by infusion of 35L tap water each, about one hour before the colonoscopy. Quality of bowel cleansing was assessed with the Boston score by an endoscopist blinded to the preparation type. Boston scores in both groups were compared with a non-parametric test, with a signifcance level of 5%.