Abstract

median of 7 EBDs before MMC was injected. After the procedure, a standard endoscope (diameter, 9.2 mm) could pass through the lesion, and DS was improved in all cases (Grade3i1 in 3 patients and Grade4i2 in 2 patients). The procedure was performed once in 2 patients and twice in 3 patients until dysphagia resolved. No serious complications related to the procedure, such as bleeding, perforation, or myelosuppression by the drug, were noted. Conclusion: Locoregional MMC injection for post-ESD strictures refractory to EBD might be feasible even in SEC cases, although an appropriate schedule of the procedure should be established in a mega-study in the future.

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