Abstract
Esophageal squamous cell carcinoma (ESCC) and high grade intraepithelial neoplasia (HGIN) are common metachronous squamous cell neoplasms that developed after ENT related squamous cell cancers (SCC) (6-9% annually). However, the incidences and risks of metachronous esophageal neoplasm may be different among those ENT related SCCs.
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