Abstract
Confocal laser microscopy is an imaging technology that integrates a confocal laser microscope in the tip of a standard videoendoscope or as a probe that can be passed through the channel of any endoscope. The aim is to provide real-time histology, allowing high resolution in vivo histological assessment at subcellular resolution during endoscopy. NBI was developed primarily to emphasize the mucosal microvasculature and to identify vascular alterations indicative of dysplasia. The accuracy in reported studies for the detection of neoplasia for both modalities has been excellent.
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