Abstract

Abdominal pain in CP may arise from an inflamed parenchyma or obstructed pancreatic duct (visceral pain). However, many patients with CP have non-visceral pain sources (central, psychogenic, or somatosensory). EUS and other imaging tests (CT, MRCP) are used to diagnose and stage CP. However, it is not known whether structural changes on imaging tests predict the presence of visceral pain which may respond to “pancreas-directed” interventions (e.g. ERCP, surgical resection). The retrograde epidural differential nerve block (DNB) attempts to distinguish visceral from non-visceral pain.

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