Abstract

treatment. 59% had one block, 13% two, 13% three, 4% four blocks and 9% five blocks. Eventually 4 patients underwent surgical intervention. Abdominal Pain intensity: Average pain decreased from 4.3 + 3 at baseline to 1.7 + 2 at first follow-up post-block (P 75% pain reduction) and 50 % complete relief. Duration of relief: 77% percent reported immediate relief after the block on the day of the procedure, 42% had relief for13 months, 20% for more than 6 months and 6.7% more than a year. Long term follow up. Taking all interventions for ACNES, at the time of the last follow up (7 + 2 months) : 52% of patients had poor abdominal pain reduction, 8% a significant reduction, 8% good reduction, 4% excellent pain reduction, and 21%were asymptomatic Associated GI symptoms after ACNES treatment: Among those with additional (non-ACNES related) GI symptoms 54% reported resolution of associated symptoms, 23% improved, 4% were worse, and 12.5% developed a new GI symptoms ( P< 0.02, compared to baseline). Conclusions: ACNES is a frequently overlooked reason for focal abdominal pain in patients diagnosed with FAP and IBS. ACNES pain may exacerbate the pain amplification related to underlying etiology and may be a treatable trigger. USG nerve block procedures are a viable treatment option, with significant immediate pain relief reported by most patients. Relapses are common and are treated with repeat blocks. A subset of patients experienced longer term relief of weeks to months. Resolution of the focal abdominal pain after treatment was also associated with improvement in other GI symptoms in a significant proportion of patients.

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