Abstract

Purpose: Extensive Monte Carlo modeling was performed using MCNP5 to characterize the Xoft AXXENT™ miniature x‐ray source for electronic brachytherapy. This study assessed the dose distribution, dosimetry parameters using the AAPM TG‐43U1 protocol, and the sensitivity of results to source geometric parameters and choices of computational parameters. Method and Materials:Monte Carlo simulations of radiation generation and transport utilized the MCNP5 code and EPDL97‐based mcplib04 cross‐section library. Dosimetry parameters using a modified TG‐43U1 2‐D dosimetry formalism were determined at 40, 45, and 50 kV operating voltages. While the source was modeled as a point due to small anode size, 30x. Conclusion: A miniature x‐ray source for electronic brachytherapy has been characterized using MCNP5. The Monte Carlo results agreed with measured results for radial dose function and anisotropy function to within ± 10%. Conflict of Interest: Research was supported by Xoft, Inc.

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