Abstract
Purpose:The inverse geometry computed tomography (IGCT) composed of multiple source and small size detector has several merits such as reduction of scatter effect and large volumetric imaging within one rotation without cone‐beam artifact, compared to conventional cone‐beam computed tomography (CBCT). By using this multi‐source characteristics, we intend to present a selective and multiple interior region‐of‐interest (ROI) imaging method by using a designed source on‐off sequence of IGCT.Methods:All of the IGCT sources are operated one by one sequentially, and each projection in the shape of narrow cone‐beam covers its own partial volume of full field of view (FOV) determined from system geometry. Thus, through controlling multi source operation, limited irradiation within ROI is possible and selective radon space data for ROI imaging can be acquired without additional X‐ray filtration. With this feature, we designed a source on‐off sequence for multi ROI‐IGCT imaging, and projections of ROI‐IGCT were generated by using the on‐off sequence. Multi ROI‐IGCT images were reconstructed by using filtered back‐projection algorithm. All these imaging process of our study has been performed by utilizing digital phantom and patient CT data. ROI‐IGCT images of the phantom were compared to CBCT image and the phantom data for the image quality evaluation.Results:Image quality of ROI‐IGCT was comparable to that of CBCT. However, the distal axial‐plane from the FOV center, large cone‐angle region, ROI‐IGCT showed uniform image quality without significant cone‐beam artifact contrary to CBCT.Conclusion:ROI‐IGCT showed comparable image quality and has the capability to provide multi ROI image within a rotation. Projection of ROI‐IGCT is performed by selective irradiation, hence unnecessary imaging dose to non‐interest region can be reduced. In this regard, it seems to be useful for diagnostic or image guidance purpose in radiotherapy such as low dose target localization and patient alignment.This research was supported by the Mid‐career Researcher Program through NRF funded by the Ministry of Science, ICT & Future Planning of Korea (NRF‐2014R1A2A1A10050270) and by the Radiation Technology R&D program through the National Research Foundation of Korea funded by the Ministry of Science, ICT & Future Planning (No. 2013M2A2A7038291)
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