Abstract

Purpose: Treating moving oragan has been an issue due to the dynamic nature of Tomotheapy. Non of study has investigated throughly the multi‐ fractional effects of treatments. Therefore, we designed a study to evaluate the cumulative error in moving target and nearby normal tissues. Methods: A moving phantom whose motion pattern could be rogrammed by a user was produced. Four plans which used different jaw width (1.05 cm, 2.5 cm), pitch (0.660, 0,287) and modulation factor (1.5, 2.5) to deliver 1.49 Gy to 95% of PTV in each fraction were made. For each plan, 5 different motions (amplitude 1–3cm, Period 3–5sec) and irregular motion were tested. Film measurements for accumulated dose were made with Gafchromic@EBT films from 1 to 5 fractions. Dose distribution on each film was compared with that measured in static phantom. Profile shapes, DoseArea Histogram (DAH)s and gamma index were used for comparison Results: The dose distortion increased up to 3rd fractions and, after 3rd fractions dose distributions in the target and OAR converged to some constant distribution. The distortion level inside the target was affected by motion parameters; larger motion amplitude and larger motion period resulted in increased dose. However dose at the center of the critical organ was rather affected by the motion amplitude than the motion period . The irregularity of the motion was not thought to cause large dose artifact. More complicated plan with larger modulation factor (2.5) resulted in larger dose distortin than the plan with modulation factor 1.5. The observed phenomena is thought to be reproducible since 3 different measurements of accumulated 5 fraction of treatments showed very similar dose distributions Conclusions: When treating moving organ in small number of fractions, verifying the dose artifact is necessary. (This work was supported by Korea Government (MEST, Grant No2010‐0011771)

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