Abstract

Purpose:To ascertain the feasibility of acquiring real time images of small lung tumors from scattered photons while undergoing radiation treatment. There are several methodologies currently used to track tumor location such as MV‐cine acquisition and kV fluoroscopy. However, MVcine offers no information parallel to the beam axis while kV fluoroscopy offers little potential for soft tissue discernability while also increasing the patient dose. This study investigates the feasibility of observing an actual simulated tumor while exploring techniques that may improve image quality.Methods:A prototype imager consisting of a gamma camera pinhole collimator and a computed radiography (CR) plate were used in conjunction with a Varian TrueBeam linac. One study consisted of a 2.5 cm diameter solid water cylinder representing a solid tumor imbedded within a lung equivalent material slab. The cylinder with the lung slab was sandwiched between 1 cm lung equivalent slabs and these were sandwiched between 2 slabs of solid water. The top water slab was 1 cm thick. The other imaging study consisted of three different density plugs, 0.46, 1.09, and 1.82 g/cm3 placed on the accelerator couch. The gantry was orientated 70° relative to the CR plate. The slabs and plugs were irradiated with 2000 MU and 500 MU respectively using the 6FFF mode.Results:The solid water plug was visually discernible in the slab phantom. The ratio of the signal coming from the higher density plugs (placed on the treatment couch) to that between the plugs increased from 1.02 to about 3.0 after subtracting the background image acquired with no plugs present.Conclusion:Preliminary results indicate that a lung tumor could be visualized with scattered radiation during treatment. Improvements in discerning an object can be enhanced by filtering out the head leakage and background scattered radiation not emanating from the imaged object.

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