STZ 유발 당뇨 백서의 지질과산화에 미치는 트레이닝과 항산화제 효과

Abstract

The purpose of this study was investigated the effect of training and antioxidant compounded administration for 6 weeks on blood glucose, lipid peroxidation, vitamin E, selenium concentration by 30minute edurance exercise in STZ induced diabetic rats. It was respectively random assigned to 12, divided into three group(training, antioxidant compounded administration and exercise, antioxidant compounded administration group respcectively). Endurance exercise test(16-17m/min) was performed at six weeks exercise method(30min, 5day/week) similarly. The follow results was obtained which was measured by experimental. Each exercise test periods, blood glucose concentration decreased any significant in post-exercise than rest. Each exercised test periods, TBARS showed any significant differences among groups. especially TBARS decreased in training group and antioxidant compounded administration training group. Each exercise test periods, vitamin E concentration in liver showed any significant differences among three groups. especially antioxidant compounded administration training group and antioxidant compounded administration group decreased in post-exercise. Each exercise test periods, selenium concentration in liver showed any significant differences among three groups. especially selenium concentration of all groups decreased in post-exercise. These results indicate that training and vitamin E, selenium compounded administration function lead to antioxidant system acceleration and inhibition of lipid peroxidation. Also, thesis suggests the possibility that transient exercise inhibit the effect of lipid peroxidation adapted in long periods training and antioxidant compound administration.