Abstract

Central sleep apnea (CSA) is characterised by a cessation of airflow in the respiratory airways during sleep due to fluctuations in respiratory drive accompanied by a cessation of respiratory muscle activity. Patients with CSA often have a Cheyne-Stokes respiration. CSA occurs in patients with various diseases including patients with heart failure (HF). It can lead to many unfavourable phenomena associated with sympathetic nervous system activation and increased mortality. Continuous positive airway pressure and other methods are used in the treatment of CSA. Recently, a new method has been developed that features stimulation of the phrenic nerve. This leads to contractions of the diaphragm and to regulation of the breathing pattern. The following paper presents the current state of knowledge on stimulation of the phrenic nerve, and its impact on respiratory parameters, physical performance and quality of life in patients with HF.

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